Mystery Of Why humans die around 80 may finally be solved
The mystery of why humans die at around 80, while other mammals live far shorter or longer lives, may finally have been solved by scientists.
Humans and animals die after amassing a similar number of genetic mutations, researchers have found, suggesting the speed of DNA errors is critical in determining the lifespan of a species.
There are huge variations in the lifespan of mammals in the animal kingdom, from South Asian rats, which live for just six months, to bowhead whales, which can survive for 200 years.
Previously, experts have suggested that size is the key to longevity, with smaller animals burning up energy more quickly, requiring a faster cell turnover, which causes a speedier decline.
But a new study from the Wellcome Sanger Institute in Cambridge suggests the speed of genetic damage could be the key to survival, with long-living animals successfully slowing down their rate of DNA mutations regardless of their size.
It helps explain how a five-inch long naked mole rat can live for 25 years, about the same as a far larger giraffe, which typically lives for 24.
When scientists checked their mutation rates, they were surprisingly similar. Naked mole rats suffer 93 mutations a year and giraffes 99.
In contrast, mice suffer 796 mutations a year and only live for 3.7 years. The average human lifespan in the study was 83.6 years, but the mutation rate was far lower at around 47.
Genetic changes, known as somatic mutations, occur in all cells and are largely harmless, but some can start a cell on the path to cancer or impair normal functioning.
Dr Alex Cagan, the first author of the study, said:
“To find a similar pattern of genetic changes in animals as different from one another as a mouse and a tiger was surprising.
But the most exciting aspect of the study has to be finding that lifespan is inversely proportional to the somatic mutation rate. This suggests that somatic mutations may play a role in ageing.”
The team analysed genetic errors in the stem cells from the intestines of 16 species of mammal and found that the longer the lifespan of a species, the slower the rate at which mutations occur.
The average number of mutations at the end of lifespan across species was around 3200, suggesting there is a critical mass of errors after which a body is unable to function correctly.
‘Ageing is a complex process’
Although the figure differed about threefold across species the variation was far less than the variation in body size, which varied up to 40,000 fold.
The researchers believe the study opens the door to understanding the ageing process, and the inevitability and timing of death.
Dr Inigo Martincorena, the senior author of the study, said:
“Ageing is a complex process, the result of multiple forms of molecular damage in our cells and tissues.
Somatic mutations have been speculated to contribute to ageing since the 1950s, but studying them has remained difficult.
With the recent advances in DNA sequencing technologies, we can finally investigate the roles that somatic mutations play in ageing and in multiple diseases.”
The research was published in the journal Nature.
See more here: yahoo.com
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Alan
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And now we have a vaccine to speed up the mutations and death.
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Gary Ashe
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Yeah Alan talk about pieces of the jigsaw coming together, they obviously think they can slow their rate down and live a 100 years or more on average, while the useless eaters an have their rate of celular mutation increases and life span shortened.
I hope they do find away to slow the rate down and people live far longer life spans, just not in the current elites life times
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Mark Tapley
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Say it isn’t so. All those mutations the evolutionists were depending on to make new “kinds” are really just the road to entropy. Not only that but geneticists now know that humans are accumulating more each generation. So contrary to Darwin’s hypothesis of gradual adaptation and improvement we see decline, infertility and senescence of the entire human genome over time. This mutational process has often been seen in pedigree dogs, many of which are now exhibiting very detrimental mutations from breeding within too small a gene pool. This problem has also been identified in several “royal” bloodlines going back to the ancient Egyptians where interbreeding accelerates the mutations.
This discovery is also further conformation that humans have not been around for hundreds of thousands of years. Accumulated mutations would have ground them to a halt a long time ago. There are ap. 5000 mutations that occur in humans. None of them are beneficial.
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Purebloodpatriot
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They are trying to jab as many people as possible so that their great reset aka depopulation plan work. If I get sick I will take my Ivermectin that I stashed just in case and leave rest to God. When i searched where I can get ivm on google I couldn’t find exactly what I was looking for. Every search query was censored. If I can save 1 person that will use this product instead of going to icu and plugged into ventilators that will burst her/his lungs. that is enough for me. I feel good when I put a spoke in big pharma’s wheel. If you want to get Ivermectin you can visit https://www.ivmcures.com
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Charles Higley
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Skip the ivermectin and the HCQ. Get ahead of the curve by taking adequate amounts of zinc, magnesium, and Vits C and D every day. Then, you will never need an ionophore as you will be already up on zinc and you immune system will have everything it needs. Also, it appear that Vit K2 along with Vit D is good at getting calcium where it needs to be.
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Alcheminister
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Well, I certainly wouldn’t use or espouse HCQ, IVM either, but I figured personal health status is what matters, so it’s quite contextual regarding what may be beneficial. And yes, vitamin D, vitamin K2, calcium and magnesium are quite related. I rarely see people mentioning mitoxhondrial support factors. Imo, varied plants/herbs are rather useful.
And people who harp on about IVM being anti-parasitic are ignorant of thousands of plants with anthelmintic (AND nutritious) properties. They also seem to miss the part where IVM and HCQ are essentially controlled opposition to the vaccines, and highly specific, also peddled based on fraud and that the likes of Bayer is associated with HCQ, Merck with IVM (and don’t forget about subsidiaries and other licensing). I mean, seemingly the sales of IVM has only increased like 10x, price doubled. It’s been a highly successful marketing campaign thanks to its supposed “suppression” and being constantly peddled everywhere, apparently.
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Mark Tapley
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Hello Alcheminister:
Yeah, like I stated, this cattle dewormer crap could be bought cheap at all the feed stores. I never heard of any ranchers that were shooting it down the cattle’s throat, taking any of it themselves. All of the big drug companies are controlled by the Black Rock (Rothschild-Rockefeller) Vanguard investment interlock. So their padding their wallet one way or the other.
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Alcheminister
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How is accumulated toxicity, deficiency, degeneration and tissue damage from thousands of factors in mostly homogenous, toxic societies and environments a mystery?
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Tom
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Not sure I trust any science anymore. Seems to me that the key to longer living is to live healthier, avoid poisons and toxins as much as possible and certainly do not use big pharma drugs, vaccines and mRNA injections. The body is capable of living 100 years or longer…it’s all the not-so-healthy habits we engage in and the toxins that weaken it.
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Macha
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I’d suggest less sunlight increases lifespan. Some monks spend most of life in bowls of monastery and an 80yr old looks 40 with s kin smooth as baby’s butt.
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Mark Tapley
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Hi Macha:
Not so sure about that. I don’t expect those pontificating pious popes are working all day in the sun either, during their many junkets in those 747’s from one palatial abode to the other as they instruct their cucked parishioners as to the dangers of climate change, the urgency of getting the graphene oxide injection and commemoration of the holy holohoax.
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