Epidemiologic Analyses on COVID-19 and Ivermectin

Image: Harvard University

Juan Chamie is a Senior Data Analyst who has been tirelessly researching and spreading the word of ivermectin since early May, 2020. Like the rest of the world, Mr. Chamie closely followed the spread of COVID-19, and his interest in ivermectin was piqued when a doctor in the Dominican Republic used the drug successfully to treat the illness.

Quickly thereafter, a major outbreak in Iquitos, Peru, and local health officials’ successful use of ivermectin to curb the disease, launched Juan’s months-long investigation into widespread efficacy of the drug. Using data as his compass, he showcased his results in stunning data visualizations, and has been using his findings to try to convince health officials and leaders across the world of the positive results of this easily-accessible, highly-affordable drug.

Juan is currently expanding his scope and analyzing data of ivermectin intervention all over the globe.

Juan Chamie lives with his wife in Cambridge, Massachusetts.

The FLCCC Alliance has used Chamie’s data analyses with his consent in their  Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19 and in the  Presentation during the FLCCC Alliance News Conference on Dec. 4, 2020, in Houston. We thank Juan for his thorough and important work in proving the efficacy of ivermectin in the prophylaxis and treatment of COVID-19 and for agreeing to use his data analyses in our publications.

Peru

Deaths, case fatalities and case incidence in population > age 60, before and after Ivermectin
States in blue started Ivermectin distribution at peak level. Lima in red started later.
Note the dramatically decreased case fatality rates among older patients with COVID-19 after ivermectin became widely distributed in those areas.

Download  Real-world evidence: The case of Peru. Causality between ivermectin and COVID-19 infection fatality rate by Juan Chamie (as PDF, published on ResearchGate, October 2020)

Update Jan 10, 2021 – Juan Chamie’s latest graphics/analyses and findings from Peru:
In August 2020, Peru launched a multimodal prevention campaign against COVID-19 and called it «Mega operación Tayta». The measures were aimed at the elderly and most risk-challenged people in society. Ivermectin was included in the prophylaxis protocol and was subsequently mass distributed. The following charts shows the true impact of this operation as several states implemented these measures. A concomitant reduction of daily deaths occured.

Mexico

Chiapas is the only state distributing ivermectin
Cases reduced

Chiapas vs every other State in Mexico (Chiapas is the only state distributing ivermectin)
Cases and Deaths significantly reduced

Update (Jan 10, 2021) – latest chart from Juan Chamie for Chiapas:

India

The state of Uttar Pradesh distributed ivermectin to about 200 Million people at peak level in September. Infection and death rates dropped faster and to lower levels than in the rest of India.

Paraguay

The government of the state of Alto Parana (blue) launched an ivermectin distribution campaign in early September. Although the campaign was officially described as a “de-worming” program, this was interpreted as a guise by the regions governor to avoid reprimand or conflict with the National Ministry of Health that recommended against use of ivermectin to treat COVID-19 in Paraguay. The program began with a distribution of 30,000 boxes of ivermectin and by October 15 there were very few cases left in the state.

Argentina

Several states are now implementing Ivermectin as part of COVID-19 treatment. So far, this is followed by an immediate flattening of the death curves and ultimately a dramatic reduction in mortality.

Brazil

The Mayor of the City of Porto Felize in Brazil, a physician, set up a single “sentinel unit” where all suspected cases of COVID-19 were sent. After evaluation and testing, all patients received a multi-drug treatment protocol which included ivermectin. Porto Felize has one of the lowest death rates of similar cities in Brazil.

Further, the mayor distributed ivermectin to 4,500 patients as a prophylaxis and reported that no one caught Covid-19. Health professionals also received a combination of prophylactic agents including ivermectin and only two cases of COVID-19 have been reported among the medical teams in the city. Finally, the mayor then began distributing ivermectin door to door in outlying neighborhoods.

The cities of Belem and Fortaleza began treating SARS-CoV-2 positive cases with ivermectin in early June. Cases (blue) were kept stable for a period, but the number of deaths (red) dropped drastically.

Two Medium Sized Towns in Southern Brazil
Ponta Grossa (population 355 k) vs Paranaguá (population 160 k)

  • Both towns are in the Eastern part of Paraná state in S. Brazil. Paranaguá is a major port, and Ponta Grossa is a major regional and agricultural center
  • Both mayors noted that in the port city of Itajaí (about 200 km to the South), there was a reduction in the severity and numbers of COVID cases. They stated in July 2020 that they would distribute IVM to the population.
  • The Establishment – including the State Accounts Tribunal (TCE) – opposed this initiative and the municipality of Ponta Grossa did not carry out this prophylactic distribution.
  • The Mayor of Paranaguá offered IVM to the people through points at major supermarkets in August, mobile distribution units and finally the municipal school system in September, with medical supervision and orientation. (He was re-elected in November 2020.)

See more here: covid19criticalcare.com

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Comments (2)

  • Avatar

    T. C. Clark

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    TrialSite News on Youtube has a no. of Ivermectin reports….including some negative information.

  • Avatar

    Robert

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    1) I have wondered about the outbreak in Manaus where the use of ivermectin should be well appreciated in Brazil.
    2) The US CDC/FDA advice against using ivermectin is based on a study which was almost constructed to yield a null result, viz ~500 Colombian patients treated at an average of 7 days of illness with a “non-statistically significant” reduction of symptoms from 14 to 12 days with treatment. Antiviral drugs work best when started as early as possible, for H1N1 influenza – Oseltamivir (Tamiflu) was only approved for initiation during the first 72 hours of symptoms, and treatment of H Zoster (shingles) is only recommended if started within 72 hours of onset of symptoms.
    3) Opinions not conforming to the authorities’ party line have been suppressed and sanctioned.

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