Swedish Pfizer Batch Analysis Confirms Heterogeneity

In epidemiology, external validity or generalizability is very important.

This means that when a finding is discovered in one population, that it is confirmed in another with the same exposure.

I was fortunate to interview Dr. Vibeke Manniche, PhD, a Danish epidemiologist who is the lead author an a recent publication comparing suspected adverse events after injection with Pfizer-BioNTech BNT162b2 COVID-19 COMIRNATY® vaccine in Sweden and Denmark.

The major findings are:

  1. Denmark highest risk batches of vaccines released December 2020 to March 2021, in Sweden the high risk batches continued to June, 2021
  2. The proportion of low risk batches where essentially nothing happens after injection was 32% in Denmark and 22% in Sweden. This is good news for the 75% of Americans who took the shot—up to a third may be in the clear.
  3. The blue high risk batches (12 overlapped with Denmark) was a larger group in Sweden and comprised 48% of the doses, much larger than the 4% in Denmark.
Manniche V, Schmeling M, Gilthorpe JD, Hansen PR. Reports of Batch-Dependent Suspected Adverse Events of the BNT162b2 mRNA COVID-19 Vaccine: Comparison of Results from Denmark and Sweden. Medicina. 2024; 60(8):1343. https://doi.org/10.3390/medicina60081343

Please listen to the entire interview and read the manuscript from Manniche et al. She is suspicious that Pfizer knew serious events including death were occuring with the early formulations and they must have made a change, possibility reducing the quantity of mRNA to lower the risks of later batches.

These findings are important for patients and clinicians to record the vaccine history and when the shots were taken, and then look up their Pfizer batch to understand the risks of what was injected into their bodies.

Many batches have had zero serious side effects and one can only hope they have by good fortune received their doses from those benign batches. These data apply to Pfizer only.

TrialSite News reviewed this paper and stated that batch heterogeneity should have called for immediate safety reviews by public health authorities, yet nothing happened.

The world deserves full analysis of all the vaccines by batch and information back to recipients about the adverse events that have occured with doses given out of their vials.

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Comments (3)

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    Tom

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    Analysis = DEATH. This only matters if you are crazy enough to take any fizer or moderna injections.

    Reply

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    Frank S.

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    Very interesting interview. The smokers’ lower susceptibility is due to the “nature” of COVID and the closely related vax make-up being less damaging to those persons with activated nicotinic receptors in their brain. The nicotine patch treatment provides the same benefit to non-smokers.

    Reply

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    Copernicus

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    Looks like Pfizer sent the “hot” batches to Sweden to punish them for not following the narrative.

    Reply

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