Study Shows Ivermectin has ‘Significant Impact’ on COVID19
A Cochrane-standard (=highest) review and meta-analysis of Ivermectin against Covid-19 by Bryant-Lawrie, now peer-reviewed and published, concludes that the evidence justifies the global adoption of this re-purposed, cheap medicine.
Background:
Repurposed medicines may have a role against the SARS-CoV-2 virus. The antiparasitic ivermectin, with antiviral and anti-inflammatory properties, has now been tested in numerous clinical trials.
Areas of uncertainty:
We assessed the efficacy of ivermectin treatment in reducing mortality, in secondary outcomes, and in chemoprophylaxis, among people with, or at high risk of, COVID-19 infection.
Data sources:
We searched bibliographic databases up to April 25, 2021. Two review authors sifted for studies, extracted data, and assessed risk of bias. Meta-analyses were conducted and certainty of the evidence was assessed using the GRADE approach and additionally in trial sequential analyses for mortality. Twenty-four randomized controlled trials involving 3406 participants met review inclusion.
Therapeutic Advances:
Meta-analysis of 15 trials found that ivermectin reduced risk of death compared with no ivermectin (average risk ratio 0.38, 95% confidence interval 0.19–0.73; n = 2438; I2 = 49%; moderate-certainty evidence). This result was confirmed in a trial sequential analysis using the same DerSimonian–Laird method that underpinned the unadjusted analysis.
This was also robust against a trial sequential analysis using the Biggerstaff–Tweedie method.
Low-certainty evidence found that ivermectin prophylaxis reduced COVID-19 infection by an average 86% (95% confidence interval 79%–91%). Secondary outcomes provided less certain evidence.
Low-certainty evidence suggested that there may be no benefit with ivermectin for “need for mechanical ventilation,” whereas effect estimates for “improvement” and “deterioration” clearly favored ivermectin use.
Severe adverse events were rare among treatment trials and evidence of no difference was assessed as low certainty. Evidence on other secondary outcomes was very low certainty.
Conclusions:
Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.
See more here: journals.lww.com
Header image: The Conversation
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Randy
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I thought the virus didn’t exist? 🤡
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Mark Tapley
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Hi Randy:
The virus doesn’t exist. That is why the CDC, big Pharma and the Jew MSM have to continually distract everyones attention from the basic fact that they have no sample of the alleged virus. Microbiologist Stephan Lanka has 1.5 million Euros on the table for anyone that can prove to the German Supreme Court that viruses even exist. Why are there no takers?
The Zionists don’t need a real pathogen any more than they do with the climate change fraud. All they need is an invisible, imaginary crisis in order to instill fear in the herd. People now are no more astute than medieval peasants or ignorant savages with their witch doctors. And it’s like Goebbels said: The bigger the lie the better.
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Ross Nixon
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Hi Mark, if the virus doesn’t exist how do they do gene sequencing on the various mutations?
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Markm Tapley
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Cellular mutations are common and the genes are inserted in various organisms. Viruses have not been proven to exist. They cannot give the gene sequence for covid 19, Swine flu, Bird flu, or AIDS. The tiny amount of gene sequence that was used to demonstrate the fake virus occurs in many organisms.
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