‘Remarkable’ recovery from COVID after megadose of vitamin C

A young Australian man who was critically ill with COVID-19 and suffering early stages of sepsis made a remarkable recovery after being given massive doses of vitamin C, according to his doctors.

Professor Rinaldo Bellomo, director of Intensive Care at Melbourne’s Austin Health, said the 40-year-old’s health had started to deteriorate significantly from COVID-19, with the man losing kidney function, and his blood pressure plummeting.

Sepsis — a life-threatening condition which occurs when the body damages its own organs while responding to an infection — was starting to take hold of his body and time was running out.

“We were dealing with somebody who was very unwell. We felt we were in a very difficult situation, and the patient’s life was under serious threat,” he said.

Professor Bellomo knew researchers at the Florey Institute had some promising experimental findings using megadose vitamin C to treat sepsis.

With the family’s consent, doctors gave the patient the same treatment the Florey researchers had trialled in animals.

he man was given an initial dose of 30 grams of sodium ascorbate (vitamin C) over 30 minutes, then a maintenance dose of 30 grams over six and a half hours.

“This is the equivalent of 5,000 oranges pumping through his veins,” Professor Bellomo said.

An over-the-counter vitamin C supplement is 500mg, meaning this megadose was 60 times the normal dosage, and had to be administered under hospital conditions.

Sepsis is a life-threatening condition that occurs when the body’s response to an infection damages its own organs and tissues.

It’s the most common cause of death in intensive care units, and a common cause of death for people gravely ill with COVID-19.

Often patients need to have limbs amputated to survive.

Professor Bellomo said after the patient had the megadose of vitamin C, the changes were “‘remarkable”.

“In a short period of time, we saw improved regulation of blood pressure, arterial blood oxygen levels and kidney function,” he said.

His temperature also improved.

“The patient was able to be taken off machine ventilation 12 days after starting sodium ascorbate treatment and discharged from hospital without any complications 22 days later,” he said.

‘This can’t be true’

The Florey Institute’s Professor Clive May had collaborated with Professor Bellomo for many years, keeping him up to date with the promising results they were seeing in the lab with the sepsis treatment.

“He didn’t believe us. He said ‘this can’t be true’,” Professor May said.

Colleague Dr Yugeesh Lankadeva sent the intensive care doctor videos of what was happening in the lab.

“When he came and when they saw it, they were all very amazed at how quickly the disease just reversed by doing this treatment.”

Researchers Dr Yugeesh Lankadeva and Professor Clive May stand back to back in an operating theatre.
Researchers Dr Yugeesh Lankadeva and Professor Clive May had
been trialling the treatment on animals.(Supplied: The Florey Institute
Of Neuroscience And Mental Health)

Professor May has been studying sepsis for almost two decades. His research, which has just been published in the journal Critical Care Medicine, showed giving megadose vitamin C to animals with sepsis could reverse the effects of the disease.

“I have never seen any treatment before this being able to do that,” he said.

“Giving this dose of vitamin C is just totally revolutionary. The response was quite remarkable.”

He said the function of the animal’s heart, kidneys, liver, lungs and brain began to significantly improve just three hours after getting the megadose of the vitamin.

“If the treatment works as well in patients as it does in our animal studies, I think it’s going to totally revolutionise the treatment of septic patients in intensive care units all over the world,” Professor May said.

But he stressed people with COVID-19 or any other illness should not try the same treatment at home.

“We don’t want people going out and buying ten bottles of Vitamin C and think it’s going to solve their problems — that would just make them feel very sick.”

Experts urge caution

While the result seems promising for the seriously ill Melbourne patient, and the animal studies, experts said previous studies using large doses of vitamin C to treat sepsis have been mixed.

Professor Simon Finfer, from the George Institute for Global Health, has been researching sepsis for more than 25 years.

“The pharmaceutical industry has spent $10 billion trying to find a magic bullet for sepsis.”

But also he said it was important to keep an open mind.

“If something is proving useful, we need to conduct trials to determine if there is a benefit or not.”

A 2020 review of scientific evidence published in the Journal of the American Medical Association found high dose vitamin C given on its own or with steroids did not provide “significant survival benefit” for patients with sepsis or septic shock.

The review found giving high dose Vitamin C “just in case” or “as a measure of last resort” could have negative consequences such as delaying proven therapies, such as prompt use of antibiotics.

New trial could bring answers

Professor Bellomo said many of the previous trials used a lower dose of vitamin C than the researchers did in both the animal study and the Austin did in the COVID-19 patient.

The amount of vitamin C given in this trial was 50 times greater than any other tried before for sepsis.

Doctors at Melbourne’s Austin Health have now begun a randomised controlled trial, giving some patients with septic shock a megadose of vitamin C and some a placebo.

Blood samples will be collected to gauge the patients’ immune response.

Researchers Dr Yugeesh Lankadeva and Professor Clive May stand in an operating theatre.
Researchers Dr Yugeesh Lankadeva and Professor Clive May’s lab results
were showing great promise.
(Supplied: The Florey Institute Of Neuroscience And Mental Health)

Researcher Dr Yugeesh Lankadeva said the trial would help establish the “optimal dose and treatment” that could be used by intensive care doctors in treating sepsis as a “potential life-saving option for patients with multi-organ failure”.

As for the Melbourne man who was able to walk out of hospital after the experimental treatment, his doctor Professor Bellomo said it’s an incentive to keep trialling this approach.

“We were encouraged, of course,” he said.

“This has provided us with further ammunition to investigate this intervention, to understand what the mechanisms might be and the extent of the achievement that might come from it.”

While Australia is doing well keeping COVID-19 under control, he said doctors from around the world have already been in touch to find out more about the megadose treatment.

Read more at www.abc.net.au

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Comments (10)

  • Avatar

    Jurg Gassmann

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    This is absolutely amazing. A miracle. Who’d’a thunk it?!
    Except that massive doses of intravenous vitamin C were part of the Chinese experts’ treatment protocol published a year ago…

    Reply

  • Avatar

    Peter Harris

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    I wish Linus Pauling were around today, he would be proud, and feel vindicated for all the work he did decades ago.

    Reply

  • Avatar

    Photios

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    Go back sixty/seventy years and see what Frederick Klenner was doing with Vitamin C.

    Reply

    • Avatar

      Binra

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      Yes. This treatment is not new – even for this condition. But because it is not accepted. It is periodically rediscovered. And covered over again.
      Klenner was stonewalled for polio success – including reversal of a paralysis. The agenda was already set under the ‘virus’ and vaccine.

      BTW this indicates toxic conditions rather than virus – though the process of toxic inflammation can fail to neutralise or flush out dead cells and bacterial processes can then generate toxic imbalances.

      Reply

  • Avatar

    Charles Higley

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    Folks, we really have to get a handle on this. There is no Covid-19 that can attack someone in 2021. In factious viruses do not hang around, they burn through the population and are done. Whatever virus or viruses that were in the last flu season that caused the widely varying symptoms all lumped together or separately to be called Covid-19 is long gone. Just the wide range of symptoms suggests a suite of viruses and there is nothing that says you cannot have more than one virus at a time.

    The media and authorities love to call this a NOVEL virus, but the fact is that it is a coronavirus the like of which we know well. They lead the public to think that the virus has a mind of its own and lurks in the shadows for a second surge. This is all crap in a bottle and the public is drinking it.

    The virus has NEVER been isolated, cultured, purified, and shown to cause this purported disease. Which also means that the PCR test CANNOT be specific for a virus they do not have. And the antibody test and vaccines suffer the same fatal flaw—THERE IS NO VIRUS AS A GOLD STANDARD.

    So, what is in the vaccines that they tell us are so good that we have to continue our lives with social distancing, masks, stupid quarantines, testing, and likely equally stupid policies by politicians? Why the vaccine, if it makes no difference?

    In Ireland, recently, 26% of the residents of a nursing home died after having the vaccine. However, using the crappy nonspecific PCR test, they determined that they all had COVID-19! How does that work? You get the vaccine and then get the virus and die. No thanks.

    Note: humans make exosomes in response to stresses of many kinds, even fear and anxiety. These exosomes also are picked up by the PCR test. Think on that.

    Reply

    • Avatar

      Herb Rose

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      Hi Charles,
      They give people a shot that causes their own cells to produce viral proteins and an antibody response to those proteins. When the people die they test and find these protein and antibodies and are surprised and /then say the patient died of COVID. When they are arrested for crimes against humanity they don’t plan to use an insanity defense but a stupidity defense.
      Herb

      Reply

  • Avatar

    Bob Donaldson’

    |

    This is correct
    Also read what Prof Sucharit Bhakdi on COVID-19 Facts and Lies says
    Search domain http://www.covidtruths.co.uk/2020/12/prof-sucharit-bhakdi-on-covid-19-facts-and-lies/https://www.covidtruths.co.uk/2020/12/prof-sucharit-bhakdi-on-covid-19-facts-and-lies/
    Article copyright: Jerm Draws Sucharit Bhakdi is a Thai-German specialist in microbiology, having studied at the universities of Bonn, Giesen, Mainz, and Copenhagen. He also studied at the Max Planck Institute Of Immunobiology And Epigenetics

    Reply

  • Avatar

    Brian James

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    Big Pharm and government’s will never do this because there is no money in it for them.

    Mar 20, 2020 How to strengthen your immune system and what is going on in the world

    A look at our clinic in Tijuana and ways to strengthen your immune system.

    https://youtu.be/zgikYVOjzpg

    Reply

  • Avatar

    tom0mason

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    The BIG thing with vitamin C is that it is a water soluble vitamin which human’s DO NOT store well and is quickly lost. Much of it is urinated away.
    Previous studies of vitamin C effects highlight that this essential vitamin is particularly effective at protecting muscles and collagen by countering the damage from ‘free radicals’ in the muscles and circulation (see https://drleonardcoldwell.com/2020/08/31/vitamin-c-could-help-older-adults-retain-muscle-mass-new-research/ and the references there). Vitamin C and Vitamin E combination appears to help overcome muscle damage after heart attacks (https://www.sciencedaily.com/releases/2019/09/190916103809.htm )
    ~~~~~~~~~~~~~~~~
    My main point is that people who are hospitalized for long periods probably have only marginal vitamin and mineral levels, especially if they are kept on drip feeds for extended periods. Water soluble vitamins are lost particularly rapidly, especially when the body is fighting infections.
    Why not have ALL drip fed patients on higher doses of vitamin C, (and vitamin B group?), after all it is cheap and in most cases an effective and beneficial adjunct to the standard treatment given to the patient.
    ~~~~~~~~~~~
    Water soluble (Very limited amounts stored in the human body) —
    Vitamins C, all the B (vitamin B1,2,3,5,6,9, and B12), Vitamin H (Biotin)

    Fat soluble (stored in the human body) —
    Vitamin A, vitamin D, vitamin E, vitamin K.

    Reply

  • Avatar

    richard

    |

    FOR IMMEDIATE RELEASE
    Orthomolecular Medicine News Service, Feb 10, 2020

    VITAMIN C AND ITS APPLICATION TO THE TREATMENT OF nCoV CORONAVIRUS
    How Vitamin C Reduces Severity and Deaths from Serious Viral Respiratory Diseases
    by Andrew W. Saul, Editor
    (OMNS February 10, 2020) Most deaths from coronavirus are caused by pneumonia. Vitamin C has been known, for over 80 years, to greatly benefit pneumonia patients.

    In 1936 Gander and Niederberger found that vitamin C lowered fever and reduced pain in pneumonia patients. [1]

    Also in 1936, Hochwald independently reported similar results. He gave 500 mg of vitamin C every ninety minutes. [2]

    McCormick gave 1000 mg vitamin C intravenously, followed by 500 mg orally every hour. He repeated the injection at least once. On the fourth day, his patient felt so well that he voluntarily resumed work, with no adverse effects. [3]

    In 1944 Slotkin and Fletcher reported on the prophylactic and therapeutic value of vitamin C in bronchopneumonia, lung abscess, and purulent bronchitis. “Vitamin C has greatly alleviated this condition and promptly restored normal pulmonary function.” [4]

    Slotkin further reported that “Vitamin C has been used routinely by the general surgeons in the Millard Fillmore Hospital, Buffalo, as a prophylactic against pneumonia, with complete disappearance of this complication.” [5]

    According to the US Centers for Disease Control, there are about 80,000 dead from annual influenzas, escalating to pneumonia, in the USA. Coronavirus is a very serious contagious disease. But contagion to a virus largely depends on the susceptibility of the host. It is well established that low vitamin C levels increase susceptibility to viruses. [6]

    Vitamin C lowers mortality
    It is one thing to be sick from a virus and another thing entirely to die from a viral-instigated disease. It must be emphasized that a mere 200 mg of vitamin C/day resulted in an 80% decrease in deaths among severely ill, hospitalized respiratory disease patients. [7]

    “Vitamin C is effective in reducing duration of severe pneumonia in children less than five years of age. Oxygen saturation was improved in less than one day.” [10]

    A single, cheap, big-box discount store vitamin C tablet will provide more than twice the amount used in the study above.

    And yes, with vitamin C, more is better.

    Frederick R. Klenner and Robert F. Cathcart successfully treated influenza and pneumonia with very high doses of vitamin C. Klenner published on his results beginning in the 1940s; [8] Cathcart beginning in the 1960s. [9] They used both oral and intravenous administration.

    A recent placebo controlled study concluded that “vitamin C should be included in treatment protocol of children with pneumonia so that mortality and morbidity can be reduced.” In this study, the majority of the children were infants under one year of age. By body weight, the modest 200 mg dose given, to tiny babies, would actually be the equivalent of 2,000-3,000 mg/day for an adult. [10]

    Although many will rightly maintain that the dose should be high, even a low supplemental amount of vitamin C saves lives. This is very important for those with low incomes and few treatment options.

    We’re talking about twenty cents’ worth of vitamin C a day to save lives now.

    References:
    1. Gander and Niederberger. Vitamin C in the handling of pneumonia.” Munch. Med. Wchnschr., 31: 2074, 1956.

    Hochwald A. Beobachtunger fiber Ascorbinsaure Wirkung bei der Krupposen Pneumonia.” Wien. Arch. f. inn. Med., 353, 1936.
    McCormick WJ. Have we forgotten the lesson of scurvy? J Applied Nutrition, 1962, 15:1 & 2, 4-12. https://www.seleneriverpress.com/historical/have-we-forgotten-the-lesson-of-scurvy/
    Slotkin & Fletcher. Ascorbic acid in pulmonary complications following prostatic surgery.” Jour. Urol., 52: Nov. 6, 1944.
    Slotkin GE. Personal communication with WJ McCormick. December 2, 1946.
    Saul AW. Nutritional treatment of coronavirus. Orthomolecular Medicine News Service, 16:6, Jan 30, 2020. http://orthomolecular.org/resources/omns/v16n06.shtml (22 references and 50 recommended papers for further reading)
    Hunt C et al. The clinical effects of Vitamin C supplementation in elderly hospitalised patients with acute respiratory infections. Int J Vitam Nutr Res 1994;64:212-19. https://www.ncbi.nlm.nih.gov/pubmed/7814237
    Klenner FR. Observations on the dose and administration of ascorbic acid when employed beyond the range of a vitamin in human pathology. J Applied Nutrition 1971, 23:3&4. http://www.doctoryourself.com/klennerpaper.html

    Klenner FR. (1948) Virus pneumonia and its treatment with vitamin C. J South Med Surg 110:36-8. https://www.seanet.com/~alexs/ascorbate/194x/klenner-fr-southern_med_surg-1948-v110-n2-p36.htm .

    Klenner, FR. (1951) Massive doses of vitamin C and the virus diseases. J South Med and Surg, 113:101-107.

    Klenner, FR. (1971) Observations on the dose and administration of ascorbic acid when employed beyond the range of a vitamin in human pathology. J. App. Nutr., 23:61-88.

    All of Dr. Klenner’s papers are listed and summarized in: Clinical Guide to the Use of Vitamin C (ed. Lendon H. Smith, MD, Life Sciences Press, Tacoma, WA, 1988. This book is posted for free access at http://www.seanet.com/~alexs/ascorbate/198x/smith-lh-clinical_guide_1988.htm

    Cathcart RF. (1981) Vitamin C, titrating to bowel tolerance, anascorbemia, and acute induced scurvy. Med Hypotheses. 7:1359-76. http://www.doctoryourself.com/titration.html

    Cathcart RF. (1993) The third face of vitamin C. J Orthomolecular Med, 7:197-200. Free access at http://www.doctoryourself.com/cathcart_thirdface.html

    Additional Dr. Cathcart papers are posted at http://www.doctoryourself.com/biblio_cathcart.html

    Khan IM et al. (2014) Efficacy of vitamin C in reducing duration of severe pneumonia in children. J Rawalpindi Med Col (JRMC). 18(1):55-57. https://www.journalrmc.com/volumes/1405749894.pdf

    Recommendations for further reading:
    A coronavirus pandemic can be stopped with the immediate widespread use of high doses of vitamin C. Preventing and treating severe respiratory infections with large amounts of vitamin C is well established. There has been a lack of media coverage of this therapeutic approach against viruses in general, and coronavirus in particular. (A Chinese language edition is also freely available.)

    The nutritional treatment of coronavirus is presented, with dosage specifics, in this protocol endorsed by physicians on the editorial board of the Orthomolecular Medicine News Service.

    Exactly how to administer intravenous vitamin C to a hospitalized patient with a viral illness, by Atsuo Yanagisawa, MD, Japanese College of Intravenous Therapy. (Here is the IV vitamin C protocol in Chinese).

    Instructions on how to take high oral doses of vitamin C during illness, by Robert F. Cathcart III, MD. This paper contains the doctor’s answers to many questions about the therapeutic use of vitamin C.

    Nutritional Medicine is Orthomolecular Medicine
    Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org

    Find a Doctor
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    Editorial Review Board:
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    Andrew W. Saul, Ph.D. (USA), Editor-In-Chief
    Editor, Japanese Edition: Atsuo Yanagisawa, M.D., Ph.D. (Japan)
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