Korean scientists restore cancer cells back to normal

Written by Jamie Manuel on January 29, 2025. Posted in Current News

For years, scientists have been working closely in the medical field to try and find different treatments for diseases––especially the most feared ones such as cancer.

Recently, a team of Korean scientists have developed a way for cancer cells to repair themselves back to normal as to improve a patient’s health. This groundbreaking discovery is spearheaded by Korea Advanced Institute of Science and Technology (KAIST) specifically targeting colon cancer.

Instead of killing cancer cells as our current treatments and procedures promise to do, the scientists at KAIST created a technology where the cancer cells would restore themselves to normal, thus avoiding side (and potentially harmful) effects.

Inspired by that notion that cancer treatments do have risky side effects, research leader Professor Kwang-Hyun Cho of Bio and Brain Engineering closely watched the process known as oncogenesis––simply put as cancer formation.

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Normal cells recede as they make their way to their differentiation trajectory, a process that determines how cells mature and specialise. From these observations, the researchers developed a digital clone of the gene network accountable for cell differentiation.

The team then proceeds to advance simulation analysis which allowed them to identify key molecular “master switches” that will eventually prompt colon cancer cells to return to the normal cell-state.

The scientists were able to prove their discovery by focusing on the fact that cancer cell reversion can happen by working closely and monitoring the digital twin of the gene network.

As published in the Advanced Science journal, Professor Cho stated that this is indeed a huge phenomenon because now we are given hope that cancer cells have the ability to ‘heal’ themselves through systematic analysis of how cells work and the introduction of the team’s technology.

This holds so much promise in the future of cancer treatments and therapies, and perhaps a faster yet safer way for patients to declare themselves cancer free. Furthermore, this also marks the beginning that different kinds of cancers may also be treated through the same cell-repairing process.

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