Breakthrough: Ivermectin inhibits Covid spike protein binding
Ivermectin, a common anti-parasite drug, has shown great efficacy in the fight against covid-19. For the first time, medical researchers have documented how ivermectin docks to the SARS-CoV-2 spike receptor-binding domain that is attached to the ACE2 receptor.
In this way, ivermectin effectively inhibits viral attachment and replication, assisting a precise antiviral response that can target the SARS-CoV-2 spike protein at its most advantageous cleavage site. The researchers showed how ivermectin interferes with the attachment of the spike protein to the human cell membrane. Ivermectin is a simple medicine derived from the bacterium Streptomyces avermitilis.
It weakens and kills parasites by interfering with their nervous system and muscle function. Ivermectin targets the glutamate-gated chloride channels in the parasite’s nerve and muscle cells, bolstering inhibitory effects in the parasite’s own neurotransmission. As the chloride ions permeate, the parasite’s cells are hyper-polarized and then paralyzed, resulting in their demise. In this study, ivermectin docked in region of leucine 91 of the spike protein and at the histidine 378 of the ACE2 receptor.
The binding energy and constancy of ivermectin was also measured and found to be sufficient at the ACE2 receptor, proving the anti-parasitic molecule a powerful force for blocking viral attachment of SARS-CoV-2.
Ivermectin blocks SARS CoV-2 at the ACE2 receptor in humans
The 17 randomized controlled trials that use ivermectin for early treatment and prophylaxis report positive effects, with an estimated improvement of 73 percent and 83 percent, respectively. Out of 37 early treatment and prophylaxis studies for ivermectin, 97 percent report positive effects. One of the studies documents how ivermectin inhibits the replication of SARS-CoV-2 in vitro and displays broad-spectrum anti-viral activity against the causative virus (SARS-CoV-2).
This study showed a 5,000-fold reduction in viral RNA after just 48 hours. The study also proves that effective treatments and prophylactics can mitigate the replication and spread of a virus thousands of times faster than the paranoid, isolationist approach of social distancing and lockdowns. If antivirals were encouraged early and often, then the spread of actual infectious virus would have been mitigated at rates thousands of times faster than the insane method of treating everyone as if they are infectious.
By treating actual infections where symptoms are present, the spread is reduced at magnitudes thousands of times greater, while conveying immunity instead of terror. The SARS-CoV-2 spike protein is designed to attach to angiotensin-converting enzyme 2 (ACE2) in humans. To see whether ivermectin could dock at this receptor site and block viral attachment, the researchers used a program called AutoDock Vina Extended. This docking study showed the crystal structure of the SARS-CoV-2 spike receptor binding domain.
The researchers looked specifically at the human ACE2 receptor and calculated the root-mean-square deviation (RMSD) of its atomic positions. A lower RMSD value indicates a more accurate docking capacity. When the RMSD value is three or greater, no docking has occurred at the receptor site. Ivermectin did not dock at nine of the locations; however, it did dock at the leucine 91 region of the spike and histidine 378 at the intersection of proteins between SARS CoV-2 and the ACE2 receptor complex.
Previous studies proved ivermectin’s efficacy, but had to use high concentrations of the drug because the study relied on African green monkey kidney epithelial cells, which do not express the human ACE2 receptor. SARS-CoV-2 is specifically equipped to infect human ACE2 receptors, so this study could prove ivermectin to be effective in much smaller dosages. Clinical trials are now underway to determine if ivermectin is an effective treatment for covid-19.
The global conspiracy to suppress effective anti-viral medicines
The World Health Organization, the FDA, and the NIH have repeatedly suggested that no antiviral treatments exist for covid-19, even though multiple antiviral herbs and drugs have been studied during previous SARS and MERS epidemics and found to be effective. This time around, many of these antivirals were used with great effectiveness by doctors who were willing to go out on a limb and save lives. Chinese hospitals used various antiviral herbs to treat covid-19 patients.
These hospitals studied the effects of the herbs for impeding virus-cell receptor binding, for stimulation of the host’s immunity, for blocking virus entry into host cells through action on the host’s enzymes, and for prevention of SARS-CoV-2 RNA synthesis and replication. The research found numerous phytochemicals to be effective, including: quercetin, ursolic acid, kaempferol, isorhamnetin, luteolin, glycerrhizin, and apigenin.
The top three most effective plants for treating covid-19 included licorice root, (Glycyrrhiza glabra) chicory root, (Cichorium intybus) and hibiscus flowers (Hibiscus sabdariffa). A number of antiviral plants contain compounds that target all three antiviral targets, including olive leaf (Olea europaea), white horehound (Marrubium vulgare), black cumin seed (Nigella sativa), garden cress (Lepidium sativum), Judean wormwood (Artemisia Judaica), guava (Psidium guajava), chrysanthemum (Glebionis coronaria), and Maryam’s flower (Anastatica).
Medical systems around the world are not properly equipped to strengthen the human immune response or understand what individuals need to overcome an infection. When it comes to fighting infections, the US FDA and European drug regulators parrot the same narrative of ignorance and apathy, withholding viable antivirals from the public.
By the way, this is the only legal way to bring experimental vaccines to the global marketplace, by proving that no effective treatments exist.
This suppression of science on antiviral treatments has paved the way for emergency use authorization of experimental vaccines and forced countless patients to suffer (and die) on ventilators, without treatment.
See more here: afinalwarning.com
Header image: The Conversation
Please Donate Below To Support Our Ongoing Work To Expose The Lies About COVID19
PRINCIPIA SCIENTIFIC INTERNATIONAL, legally registered in the UK as a company 
incorporated for charitable purposes. Head Office: 27 Old Gloucester Street, London WC1N 3AX.
Trackback from your site.
dnomsed
| #
Bravo…
Reply
Herb Rose
| #
If Ivermectin can prevent spike proteins from binding to cells there is hope for those who got the vaccine. They’ll need to take it for the rest of their lives.
Reply
Townsin2
| #
Hopefully. Many loved ones who have taken the jab.
Reply
Mark Tapley
| #
Hi Herb:
There is very little hope for the chronically stupid, asininely gullible idiots that took the Rockefeller blood toxin injection. Any one that believes anything the Zionist controlled Jew MSM tell them is an idiot. When my wife showed me the facebook post on her phone of the just staged Fake Floyd psyop I told her “Judy your an idiot.” So are all the simps taking this cattle dewormer for the poison injection. They might as well shove it up their ass. You can bet that the insiders are making a killing on this crap. The real problem here is that the great mass of goyim are going to drag all of us down with them into the Zionists Neo feudal tyranny. And they have a place for you too Herb.
Reply
Yvonne Bodinger
| #
I live in Spain. Can you buy it in any country?
Reply
Yvonne Bodinger
| #
IWhere can you buy Ivermectin?
Reply
Mac
| #
A physician can prescribe or 1% Ivermectin injectible solutions are available at farm animal supply stores, coops, vet supply, etc. The solution may be drank at a 1cc per 110 lbs body weight for proper dosing. The FLCCC website gives the full protocol for both prophylaxis and treatment.
Reply
Yvonne Bodinger
| #
I have not got an answer on where I can buy this medicine
Reply
Mark Tapley
| #
Hello Yvonne:
For many years you could buy this cattle dewormer at the local feed stores or when the Tractor Supply stores opened (which are kind of a cross between at bad hardware store and a bad feed store) they handled it. They carry nitch items for rural areas such as rat bait, tee posts, and cheap dog food that Wal Mart doesn’t;t bother with. Now that all the idiots that got the Rockefeller blood toxin injection are chasing another Jew MSM fabrication it is probably requires a prescription from a medical shill and is a hundred times higher.
All of this is a racket. Just like the cancer therapy where big Pharma is selling 0.10 cent pills to cancer patients for a 2000% profit that don;’t do anything anyway. The cancer industry is where the current covid scam began. After 30 years of the “War on cancer” Fauci and the Rockefeller CDC could no longer keep beating a dead horse with absolutely no results for the patients, So the CDC and big Pharma had our aIPAC shabbas goy legislators pass the Bayh Dole Act (you can read it) that allowed for the invention of the phony AIDS scam that brought in many billions of dollars to the insiders . After several other fake viruses they are now cashing in on the fake covid.
Reply
Yvonne Bodinger
| #
I don’t think I have got an answer to where I can get this medicine
Reply
Greg
| #
I got mine online do a duckduck go search,12mg pills are what you are looking for. I feel like a new man after 6 doses!
Reply
Greg
| #
Stromectol Is what it’s marketed under in Europe here in the states you need a prescription.
Reply