IV injection of COVID mRNA vaccine can induce acute myopericarditis

Post-vaccination myopericarditis is reported after immunization with COVID-19 mRNA-vaccines. The effect of accidental intravenous injection of this vaccine on the heart is unknown.

METHODS: We compared the clinical manifestations, histopathological changes, tissue mRNA expression and serum levels of cytokine/chemokine in Balb/c mice at different time points after intravenous(IV) or intramuscular(IM) vaccine injection with normal saline(NS) control.

RESULTS: Though significant weight loss and higher serum cytokine/chemokine levels were found in IM group at 1 to 2 days post-injection(dpi), only IV group developed histopathological changes of myopericarditis as evidenced by cardiomyocyte degeneration, apoptosis and necrosis with adjacent inflammatory cell infiltration and calcific deposits on visceral pericardium, while evidence of coronary artery or other cardiac pathologies was absent.

SARS-CoV-2 spike antigen expression by immunostaining was occasionally found in infiltrating immune cells of the heart or injection site, in cardiomyocytes and intracardiac vascular endothelial cells, but not skeletal myocytes.

The histological changes of myopericarditis after the first IV-priming dose persisted for 2 weeks and were markedly aggravated by a second IM- or IV-booster dose.

Cardiac tissue mRNA expression of IL-1β, IFN-β, IL-6 and TNF-α increased significantly from 1dpi to 2dpi in IV but not IM group, compatible with presence of myopericarditis in IV group.

Ballooning degeneration of hepatocytes was consistently found in IV group. All other organs appeared normal.

CONCLUSIONS: This study provided in-vivo evidence that inadvertent intravenous injection of COVID-19 mRNA-vaccines may induce myopericarditis. Brief withdrawal of syringe plunger to exclude blood aspiration may be one possible way to reduce such risk.

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Comments (2)

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    itsme

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    ‘Brief withdrawal of syringe plunger to exclude blood aspiration may be one possible way to reduce such risk.’

    how about……just don’t jab.

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    Rad1

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    It is impossible, if you watch television, to avoid seeing SARS-CoV-2 “vaccine” injections being given into the deltoid muscle. Of the many dozens I have seen, very few of the injectors actually pull back on the plunger to demonstrate that the end of the needle is not in a blood vessel. The purpose of this is to avoid giving an intravenous injection of material which should only be given intramuscularly. The above article supports my concern. Of course, even if these injections were to be given properly, there are many other concerns about the materials being injected, their effectiveness, and their long term adverse consequences, which are completely unknown. (According to VAERS data there is plenty of concern for damage from these injections in the short term).

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